Distinguish between diabetic ketoacidosis and HONK.?


To answer your question simply, HONK is just a change in the osmotic pressure of your blood due to increased blood sugar. The acidity of your blood is not affected because lipolysis is not being performed. In DKA, however, the body must perform lipolysis in order to survive, which increases the acidity of the blood. Below, i will explain further.

HONK is "hyperosmotic non-ketotic acidosis". Ketosis is absent in HONK because the presence of some insulin inhibits lipolysis (the conversion of fat to energy), unlike diabetic ketoacidosis which happens in the presence of very little to no insulin at all.

HONK basically just causes severe diuretic conditions in the body which case frequent urination, and causes the blood to thicken, and become more viscous. This in turn increases the osmotic pressure of your blood. The body is still able to synthesize energy from carbohydrates using the amount of insulin that it is provided. Since it does not have to perform lipolysis on a large enough scale to cause ketones to acidify the blood, it is not considered the same as diabetic ketoacidosis. Ultimately, if untreated, HONK will lead to death, just as DKA will.

Symptoms of HONK:
-Hyperviscosity and increased risk of thrombosis
-Disturbed mentation
-Neurologic signs including focal signs such as sensory or motor impairments or focal seizures or motor abnormalities, including flacidity, depressed reflexes, tremors or fasciculations.

Symptoms of DKA:
-Sluggish, extreme tiredness.
-Extreme thirst, despite large fluid intake.
-Constant urination
-Fruity smell to breath, similar to nail polish remover or peardrops.
-Hyperventilation, at first rapid and shallow, then progressively deeper and less rapid.
-Extreme weight-loss.
-Oral Thrush may be present, or/ yeast infections that fail to go away, this is because the normal fungal/flora present in oral cavity/cervix in women, the balance is upset and bacterial began to feast on the high sugar from urine output/ dry mouth from extreme thirst.
-Muscle wasting.
-Agitation / Irritation / Aggression / Confusion

2 thoughts on “Distinguish between diabetic ketoacidosis and HONK.?

  1. HONK is the sound your car makes when you press on the horn. Diabetic Ketoacidosis is when your body does not have enough insulin and blood sugars are sky high, body is producing ketones and you are withering away to nothing.
    References :

  2. To answer your question simply, HONK is just a change in the osmotic pressure of your blood due to increased blood sugar. The acidity of your blood is not affected because lipolysis is not being performed. In DKA, however, the body must perform lipolysis in order to survive, which increases the acidity of the blood. Below, i will explain further.

    HONK is "hyperosmotic non-ketotic acidosis". Ketosis is absent in HONK because the presence of some insulin inhibits lipolysis (the conversion of fat to energy), unlike diabetic ketoacidosis which happens in the presence of very little to no insulin at all.

    HONK basically just causes severe diuretic conditions in the body which case frequent urination, and causes the blood to thicken, and become more viscous. This in turn increases the osmotic pressure of your blood. The body is still able to synthesize energy from carbohydrates using the amount of insulin that it is provided. Since it does not have to perform lipolysis on a large enough scale to cause ketones to acidify the blood, it is not considered the same as diabetic ketoacidosis. Ultimately, if untreated, HONK will lead to death, just as DKA will.

    Symptoms of HONK:
    -Hyperviscosity and increased risk of thrombosis
    -Disturbed mentation
    -Neurologic signs including focal signs such as sensory or motor impairments or focal seizures or motor abnormalities, including flacidity, depressed reflexes, tremors or fasciculations.

    Symptoms of DKA:
    -Sluggish, extreme tiredness.
    -Extreme thirst, despite large fluid intake.
    -Constant urination
    -Fruity smell to breath, similar to nail polish remover or peardrops.
    -Hyperventilation, at first rapid and shallow, then progressively deeper and less rapid.
    -Extreme weight-loss.
    -Oral Thrush may be present, or/ yeast infections that fail to go away, this is because the normal fungal/flora present in oral cavity/cervix in women, the balance is upset and bacterial began to feast on the high sugar from urine output/ dry mouth from extreme thirst.
    -Muscle wasting.
    -Agitation / Irritation / Aggression / Confusion
    References :
    http://en.wikipedia.org/wiki/Diabetic_ketoacidosis#Symptoms_and_Signs
    http://en.wikipedia.org/wiki/Nonketotic_hyperosmolar_coma

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